Search results for "medical treatment"

showing 10 items of 63 documents

The Use of Medicinal Clay from Silesia “Terra sigillata Silesiaca”, Central Europe - A New Chance for Natural Medicine?

2019

Silesia is a region in Central Europe with beneficial conditions for the presence of clay, including those with potential therapeutic efficacies, due to its very diverse and mosaic geological landscape. The first use of clay deposits in medicine in Silesia, “terra sigillata Silesiaca”, has been dated to 1550 AD, and the oldest written information related to this use has been dated to 1586 AD. Medicinal clay is formed by the accumulation of a mixture of minerals such as smectite, bentonite, montmorillonite, kaolinite, illite, and metahaloisite, with impurities of other minerals and fractions, resulting from the chemical weathering of rocks and the sedimentation of detritus. The quantitative …

010506 paleontologyGeographyPeloids; Medicinal clays; Silesia; Balneotherapy; Medical treatment060102 archaeology0601 history and archaeologyMedicinal clay06 humanities and the artsGeneral MedicineSedimentation01 natural sciencesNatural medicineArchaeology0105 earth and related environmental sciencesBiomedical Journal of Scientific & Technical Research
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Predictive factors of response to mTOR inhibitors in neuroendocrine tumours

2016

Medical treatment of neuroendocrine tumours (NETs) has drawn a lot of attention due to the recent demonstration of efficacy of several drugs on progression-free survival, including somatostatin analogs, small tyrosine kinase inhibitors and mTOR inhibitors (or rapalogs). The latter are approved as therapeutic agents in advanced pancreatic NETs and have been demonstrated to be effective in different types of NETs, with variable efficacy due to the development of resistance to treatment. Early detection of patients that may benefit from rapalogs treatment is of paramount importance in order to select the better treatment and avoid ineffective and expensive treatments. Predictive markers for th…

0301 basic medicineOncologyCancer ResearchmTOR inhibitorEndocrinology Diabetes and MetabolismNeuroendocrine tumorsAntineoplastic Agent0302 clinical medicineEndocrinologyNeuroendocrine tumoursneuroendocrine tumourTreatment resistanceMTOR inhibitorsTumorMedical treatmentTOR Serine-Threonine KinasesDiscovery and development of mTOR inhibitorsResponse to treatmentPatient managementDiabetes and MetabolismNeuroendocrine TumorsOncology030220 oncology & carcinogenesisResponse to treatmentNeuroendocrine TumorHumanMTOR inhibitors; Neuroendocrine tumours; Predictors; Response to treatment; Animals; Antineoplastic Agents; Biomarkers Tumor; Diagnostic Imaging; Humans; Neuroendocrine Tumors; Protein Kinase Inhibitors; TOR Serine-Threonine Kinases; Endocrinology Diabetes and Metabolism; Oncology; Endocrinology; Cancer ResearchDiagnostic Imagingmedicine.medical_specialtyProtein Kinase InhibitorEarly detectionpredictorAntineoplastic AgentsMTOR inhibitors; Neuroendocrine tumours; Predictors; Response to treatment; Endocrinology; Oncology; Cancer Research; Endocrinology Diabetes and MetabolismBiologyNO03 medical and health sciencesmTOR inhibitors; neuroendocrine tumours; predictors; response to treatment; Animals; Antineoplastic Agents; Biomarkers Tumor; Diagnostic Imaging; Humans; Neuroendocrine Tumors; Protein Kinase Inhibitors; TOR Serine-Threonine KinasesInternal medicineBiomarkers TumormedicineAnimalsHumansmTOR inhibitorsneuroendocrine tumourspredictorsresponse to treatmentProtein Kinase InhibitorsmTOR inhibitors neuroendocrine tumours predictors response to treatmentAnimalPredictorsmedicine.disease030104 developmental biologyImmunologyBiomarkersResource utilizationEndocrine-Related Cancer
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At-home laser treatment of oral neuronal disorders : case reports

2017

The neuronal disorders occurring in the oral district are mainly anaesthesia, paraesthesia, hypoesthesia and hyperaesthesia and they may occur frequently after surgical procedures. Medical treatment depends on degree of severity of the nerve injury but, in every case, it must be immediately carried out to reduce immune inflammatory reaction. The aim of this report is to investigate the effectiveness in the recovery of the peripheral nerve lesions of a new laser device recently proposed by the commerce that, due to its reduced size and to be a class I laser according the ANSI classification, may be used at home by the patient himself. Three different cases were treated with this "at-home app…

0301 basic medicinemedicine.medical_specialtyOral Medicine and PathologyMedical treatmentSide effectbusiness.industrymedicine.medical_treatmentLaser treatmentCase Report030206 dentistryHypoesthesiaNerve injury:CIENCIAS MÉDICAS [UNESCO]Surgery03 medical and health sciences030104 developmental biology0302 clinical medicineReduced sizePeripheral nerveUNESCO::CIENCIAS MÉDICASmedicinemedicine.symptombusinessGeneral DentistryLow level laser therapy
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Cirugía de la mano reumática: nuevas expectativas para una vieja conocida

2017

ResumenEs importante que todos los especialistas que tratan a pacientes afectados de artritis reumatoide (AR), conozcan las distintas opciones terapéuticas disponibles, tanto médicas como quirúrgicas, y su manejo en las distintas fases del tratamiento. Nuestro objetivo es actualizar lo que como cirujanos debemos saber sobre el tratamiento médico de la enfermedad, cómo manejar los fármacos durante la programación de la cirugía y cuál es la evidencia sobre las distintas opciones quirúrgicas que podemos barajar ante diversas situaciones originadas por un aparente mismo patrón: la sinovitis.

030203 arthritis & rheumatology030222 orthopedicsEconomics and EconometricsMedical treatmentbusiness.industrylcsh:SurgeryForestrylcsh:RD1-811cirugía03 medical and health sciences0302 clinical medicinetratamiento médicoMaterials ChemistryMedia TechnologyMedicinebusinessHumanitiesartritis reumatoideRevista Iberoamericana de Cirugía de la Mano
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Blunt force trauma: an exceptional example of an ancient Egyptian mummy head

2019

In the course of a scientific cooperation between the German Mummy Project at the Reiss-Engelhorn-Museen, Mannheim (Germany) and the Musée National d'Histoire et d'Art Luxembourg (Luxembourg), an ancient Egyptian mummy head was analyzed using a multidisciplinary approach including radiocarbon dating, ultra-high resolution computed tomography, physical anthropology, forensic medicine and Egyptology. Dated to the Roman Period, the mummy head belonged to an upper-class woman between 25 and 35 years of age. Computed tomography revealed a lethal blunt force trauma affecting the dorsal parts of the parietal bones, below the intact overlaying soft tissue. Moreover, ancient medical treatment was ev…

AdultHistoryMedical treatmentEgypt AncientBiological anthropologyPoison controlForensic anthropologyMummiesGeneral MedicineAncient historyWounds NonpenetratinghumanitiesHead (geology)EgyptologyBluntHomicideAnthropologyCraniocerebral TraumaHumansFemaleAnimal Science and ZoologyHeadHistory AncientEcology Evolution Behavior and SystematicsAnthropologischer Anzeiger
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Intoxication with a tropenol ester.

2012

BACKGROUND While the effects of medicinal products are investigated in depth before approval, often very little is known about the intermediates occurring during synthesis. The pharmacological properties of these intermediates can differ substantially from those of the end product. AIMS To describe a work accident involving intoxication with such an intermediate, tropenol ester. CASE REPORT A healthy 40-year-old chemical-technical operative erroneously used a scrubbing brush that had just been used to clear up tropenol ester, contaminating his work clothes. Presumably, contact was made with his skin when removing his work clothes later. Shortly thereafter, he developed signs of anticholiner…

AdultMaleMedical treatmentTertiary aminebusiness.industrymedicine.drug_classMydriasisPublic Health Environmental and Occupational HealthAntagonistEstersAnticholinergic agentsMuscarinic AntagonistsCholinergic AntagonistsSeizuresAnesthesiaOccupational ExposureToxicityMuscarinic acetylcholine receptorAnticholinergicMydriasisMedicineHumansAtaxiamedicine.symptombusinessOccupational medicine (Oxford, England)
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Treatment of central and sensorineural tinnitus with orally administered Melatonin and Sulodexide: personal experience from a randomized controlled s…

2008

Since very little is understood about the exact aetiology of tinnitus, this has made treatment of the condition difficult. Even though approximately 10-15% of the general population suffer from tinnitus, only 2% consider it serious enough to warrant any treatment. The main problem arising from tinnitus is the disturbance it causes not only in day to day life but also in sleep, leading to fatigue and general discomfort. The present study focused on the effect of Melatonin in conjunction with Sulodexide as a treatment method for tinnitus. Overall, 102 patients suffering from tinnitus were evaluated in a prospective randomised controlled study conducted in a tertiary care ENT department. After…

AdultMaleMelatonin sulodexideAcufenometryAdministration OralTinnitus handicap inventoryOtologyHearing lossMiddle AgedTinnitusotorhinolaryngologic diseasesHumansFemaleProspective StudiesMedical treatmentGlycosaminoglycansMelatoninActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale
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Short-and long-term outcome after PTCA in patients with stable and unstable angina

1990

Acute results and follow-up data over a period of 36 months after attempted PTCA in 406 patients with stable angina and 202 patients with unstable angina are reported. The rate of acute complications (death, myocardial infarction and bypass grafting (CABG) amounted to 1.5% in stable and 6.4% in unstable patients (P less than 0.005). Within the first week after PTCA a significantly lower percentage (1.7% vs 10.4%) of cardiac events (death, myocardial infarction, CABG and repeat PTCA) was observed in the stable group (P less than 0.001). During a 12-month follow-up period, another 16.3% of the patients in the stable group and 30.7% of unstable patients suffered a new cardiac event (P less tha…

AdultMalemedicine.medical_specialtyBypass graftingMyocardial InfarctionAsymptomaticAngina PectorisPostoperative ComplicationsInternal medicinemedicineHumansIn patientAngina Unstablecardiovascular diseasesMyocardial infarctionAngioplasty Balloon CoronaryCoronary Artery BypassMedical treatmentUnstable anginabusiness.industryIncidence (epidemiology)Middle AgedPrognosismedicine.diseaseQuality of LifeCardiologyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessEarly phaseFollow-Up StudiesEuropean Heart Journal
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The medical treatment with pasireotide in Cushing’s disease: an Italian multicentre experience based on “real-world evidence”

2019

A phase III study has demonstrated that 6-month pasireotide treatment induced disease control with good safety in 15–26% of patients with Cushing’s disease (CD). The aim of the current study was to evaluate the 6-month efficacy and safety of pasireotide treatment according to the real-world evidence. Thirty-two CD patients started pasireotide at the dose of 600 µg twice a day (bid) and with the chance of up-titration to 900 µg bid, or down-titration to 450 or 300 µg bid, on the basis of urinary cortisol (UC) levels or safety. Hormonal, clinical and metabolic parameters were measured at baseline and at 3-month and 6-month follow-up, whereas tumour size was evaluated at baseline and at 6-mont…

AdultMalemedicine.medical_specialtyHydrocortisoneEndocrinology Diabetes and MetabolismUrinary system030209 endocrinology & metabolismDiseaseSomatostatin analoguesCushing’s disease; Medical treatment; Pasireotide; Pituitary tumour; Somatostatin analoguesBody Mass IndexYoung Adult03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyInternal medicineDiabetes mellitusHumansMedicinePituitary NeoplasmsPituitary ACTH HypersecretionAdverse effectAgedmedicine.diagnostic_testbusiness.industryPituitary tumourCushing's diseaseMiddle AgedCushing’s diseasemedicine.diseaseMagnetic Resonance ImagingPasireotidePasireotideTreatment OutcomeItalychemistry030220 oncology & carcinogenesisCushing’s disease Medical treatment Pasireotide Pituitary tumour Somatostatin analoguesFemaleOriginal ArticleWaist CircumferenceSomatostatinbusinessLipid profileBody mass indexMedical treatment
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Contemporary Management of Struvite Stones Using Combined Endourologic and Medical Treatment: Predictors of Unfavorable Clinical Outcome

2016

Struvite stones have been associated with significant morbidity and mortality, yet there has not been a report on the medical management of struvite stones in almost 20 years. We report on the contemporary outcomes of the surgical and medical management of struvite stones in a contemporary series.A retrospective review of patients who were treated with percutaneous nephrolithotomy (PCNL) for struvite stones at Duke University Medical Center between January 2005 and September 2012 identified a total of 75 patients. Of these, 43 patients had adequate follow-up and were included in this analysis. Stone activity, defined as either stone recurrence or stone-related events, and predictors of acti…

AdultMalemedicine.medical_specialtyStruviteUrologymedicine.medical_treatment030232 urology & nephrologyComorbidityHydroxamic AcidsKidney CalculiYoung Adult03 medical and health scienceschemistry.chemical_compoundPostoperative Complications0302 clinical medicineRecurrencePotassium CitratemedicineHumansUniversity medicalEnzyme InhibitorsDiureticsPercutaneous nephrolithotomyAgedNephrostomy PercutaneousRetrospective StudiesAged 80 and overRetrospective reviewMedical treatmentbusiness.industryChlorthalidoneRetrospective cohort studyMiddle Agedmedicine.diseaseComorbidityAnti-Bacterial AgentsSurgerySodium BicarbonateTreatment OutcomechemistryStruvite030220 oncology & carcinogenesisNephrostomyFemaleCalcium CitratebusinessJournal of Endourology
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